Questão 506675

Analyze the text regarding bioethics and genetic governance:

'The advent of germline genome editing tools, notably CRISPR-Cas platforms, has dissolved the clear demarcation between therapeutic intervention and human genetic enhancement. While somatic therapies target non-heritable genetic anomalies within existing patients, germline alterations introduce modifications into the reproductive lineage, transmitting synthetic genetic traits to future generations. This reality has catalyzed calls for a binding global moratorium until consensus on safety and equity is reached.'

Judge the following statements:

I. Somatic therapies introduce genetic modifications that are inherited by subsequent generations.

II. Germline editing alters the human reproductive lineage, permanently transferring genetic modifications to descendants.

III. A global moratorium has been universally dismissed because therapeutic modifications carry no bioethical concerns.

Which item(s) is/are CORRECT?