Questão 1557215

“Both systematic reviews included longitudinal cohort studies used to provide data that are mixed in terms of adverse outcomes in infants exposed to prenatal marijuana during pregnancy. These include the Ottawa Prenatal Prospective Study (OPPS), a longitudinal cohort study of low-risk, white, predominantly middle-class families; the Maternal Health Practices and Child Development Study (MHPCD), a cohort study of high-risk, low socioeconomic–status women, representing both white and African American women (...). Researchers of the MHPCD have observed a cohort of exposed infants since 1982 to determine the independent effects of marijuana on cognition, behavior, temperament, mental health disorders, and substance use from infancy through adolescence and early adulthood. At 9 months of age, impaired mental development was seen. At 3, 4, and 6 years of age, deficits in executive function tasks similar to those observed in the OPPS, with poorer memory and verbal measures were found; at 6 years of age, impaired sustained attention on vigilance tasks and verbal reasoning and increased impulsivity and hyperactivity was observed with those exposed during the first trimester whose mothers smoked at least 1 joint per day. Adverse consequences in later childhood included impaired executive functioning and visual problem-solving at 9 through 12 years of age and increased hyperactivity, impulsivity, and inattention at 10 years of age for those whose mothers had smoked marijuana during both the first and third trimesters. Unlike the OPPS, whose authors did not find deficits in intellectual abilities and on measurements of standardized academic tests at ages 6 through 9 or 13 through 16 years, authors of the MHPCD did find lower reading and spelling scores in 10-year-old children whose mothers reported smoking at least 1 joint per day during the first trimester of pregnancy and deficits in reading comprehension and underachievement, as measured by the Wide Range Achievement Test–Revised, with mothers who reported smoking marijuana during the second trimester. Lower global achievement, reading, spelling, and math scores were also seen at 14 years of age.’

Segundo o texto, extraído de “Marijuana Use During Pregnancy and Breastfeeding: Implications for Neonatal and Childhood Outcomes Sheryl A. Ryan, MD et al. Committee on Substance use and Prevention, Section on Breastfeeding”, é correto afirmar: